Endocrine Abstracts

ObjectiveThere is large inter-individual variation in the growth hormone (GH) response to resistance exercise, but the intra-individual variation is unknown. This study aimed to determine the reproducibility of the GH response to a 30-min resistance exercise session.DesignFollowing local Ethics Committee approval, nine male participants were familiarised before completing three trials in a random order. Durin...

Hyponatraemia is a well-recognised neurosurgical complication, but the incidence and complications are unknown.Objective : We aimed to define the incidence, pathophysiology and effects of significant hyponatraemia following neurosurgical admissions.Methods: All neurosurgical patients with significant hyponatraemia (plasma sodium <130 millimol per litre) between January 2002 and September 2003 were identified from computerised la...

Lithium is used in psychiatric practice as maintenance therapy in bipolar disorder. It has a narrow therapeutic index with serious toxic potential. Lithium is associated with multiple endocrine and metabolic disturbances but data regarding the rates of these in individual patients is lacking. In a tertiary referral centre, all patients on lithium therapy from 2000 to 2014 were identified. The aim of this study was to assess the impact of lithium therapy on the development of e...